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1

Familial adenomatous polyposis-associated and sporadic pyloric gland adenomas of the upper gastrointestinal tract share common genetic features

Hashimoto, Taiki, Ogawa, Reiko, Matsubara, Akiko, Taniguchi, Hirokazu, Sugano, Kokichi, Ushiama, Mineko, Yoshida, Teruhiko, Kanai, Yae, Sekine, Shigeki

Journal:

Year:

2015

Language:

english

File:

PDF, 1.30 MB

english, 2015

2

Frequent lack of GNAS mutations in colorectal adenocarcinoma associated with GNAS -mutated villous adenoma

Sekine, Shigeki, Ogawa, Reiko, Oshiro, Taihei, Kanemitsu, Yukihide, Taniguchi, Hirokazu, Kushima, Ryoji, Kanai, Yae

Journal:

Genes, Chromosomes and Cancer

Year:

2014

Language:

english

File:

PDF, 419 KB

english, 2014

3

Human amniotic fluid stem cells have a unique potential to accelerate cutaneous wound healing with reduced fibrotic scarring like a fetus

Fukutake, Marie, Ochiai, Daigo, Masuda, Hirotaka, Abe, Yushi, Sato, Yu, Otani, Toshimitsu, Sakai, Shigeki, Aramaki-Hattori, Noriko, Shimoda, Masayuki, Matsumoto, Tadashi, Miyakoshi, Kei, Kanai, Yae, K

Journal:

Year:

2018

Language:

english

File:

PDF, 2.42 MB

english, 2018

4

Genome-wide DNA methylation profiles in urothelial carcinomas and urothelia at the precancerous stage

Naotaka Nishiyama, Eri Arai, Yoshitomo Chihara, Hiroyuki Fujimoto, Fumie Hosoda, Tatsuhiro Shibata, Tadashi Kondo, Taiji Tsukamoto, Sana Yokoi, Issei Imoto, Johji Inazawa, Setsuo Hirohashi, Yae Kanai

Journal:

Year:

2010

Language:

english

File:

PDF, 2.35 MB

english, 2010

5

DNA HYPOMETHYLATION ON PERICENTROMERIC SATELLITE REGIONS SIGNIFICANTLY CORRELATES WITH LOSS OF HETEROZYGOSITY ON CHROMOSOME 9 IN UROTHELIAL CARCINOMAS

NAKAGAWA, TOHRU, KANAI, YAE, USHIJIMA, SAORI, KITAMURA, TADAICHI, KAKIZOE, TADAO, HIROHASHI, SETSUO

Journal:

The Journal of Urology

Year:

2005

Language:

english

File:

PDF, 447 KB

english, 2005

6

Frequent GNAS and KRAS mutations in pyloric gland adenoma of the stomach and duodenum

Matsubara, Akiko, Sekine, Shigeki, Kushima, Ryoji, Ogawa, Reiko, Taniguchi, Hirokazu, Tsuda, Hitoshi, Kanai, Yae

Journal:

The Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 532 KB

english, 2013

7

ADAM9 is over-expressed in human ovarian clear cell carcinomas and suppresses cisplatin-induced cell death

Ueno, Mari, Shiomi, Takayuki, Mochizuki, Satsuki, Chijiiwa, Miyuki, Shimoda, Masayuki, Kanai, Yae, Kataoka, Fumio, Hirasawa, Akira, Susumu, Nobuyuki, Aoki, Daisuke, Okada, Yasunori

Journal:

Year:

2018

Language:

english

File:

PDF, 1.76 MB

english, 2018

8

The Japanese Society of Pathology Guidelines on the handling of pathological tissue samples for genomic research: Standard operating procedures based on empirical analyses

Kanai, Yae, Nishihara, Hiroshi, Miyagi, Yohei, Tsuruyama, Tatsuhiro, Taguchi, Kenichi, Katoh, Hiroto, Takeuchi, Tomoyo, Gotoh, Masahiro, Kuramoto, Junko, Arai, Eri, Ojima, Hidenori, Shibuya, Ayako, Yo

Journal:

Pathology International

Year:

2018

Language:

english

File:

PDF, 8.80 MB

english, 2018

9

The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas

Yae Kanai, Saori Ushijima, Ai-Min Hui, Atsushi Ochiai, Hitoshi Tsuda, Michiie Sakamoto, Setsuo Hirohashi

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 214 KB

english, 1997

10

DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers

Yae Kanai, Saori Ushijima, Yutaka Kondo, Yukihiro Nakanishi, Setsuo Hirohashi

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 142 KB

english, 2001

11

Clinicopathologic significance of dysadherin expression in cutaneous malignant melanoma : Immunohistochemical analysis of 115 patients

Aya Nishizawa, Yukihiro Nakanishi, Kimio Yoshimura, Yuko Sasajima, Naoya Yamazaki, Akifumi Yamamoto, Katsumi Hanada, Yae Kanai, Setsuo Hirohashi

Journal:

Year:

2005

Language:

english

File:

PDF, 300 KB

english, 2005

12

Genetic inactivation of the APC gene contributes to the malignant progression of sporadic hepatocellular carcinoma: A case report

Hiroto Katoh, Tatsuhiro Shibata, Akiko Kokubu, Hidenori Ojima, Tomoo Kosuge, Yae Kanai, Setsuo Hirohashi

Journal:

Genes, Chromosomes and Cancer

Year:

2006

Language:

english

File:

PDF, 984 KB

english, 2006

13

Prostate stem cell antigen, a presumable organ-dependent tumor suppressor gene, is down-regulated in gallbladder carcinogenesis

Hiroe Ono, Nobuyoshi Hiraoka, Yeon-Su Lee, Sang Myung Woo, Woo Jin Lee, Il Ju Choi, Akira Saito, Kazuyoshi Yanagihara, Yae Kanai, Sumiko Ohnami, Fumiko Chiwaki, Hiroki Sasaki, Hiromi Sakamoto, Teruhik

Journal:

Genes, Chromosomes and Cancer

Year:

2012

Language:

english

File:

PDF, 589 KB

english, 2012

14

DNA hypermethylation at the D17S5 locus and reduced HIC-1mRNA expression are associated with hepatocarcinogenesis

Yae Kanai, Ai-Min Hui, Lin Sun, Saori Ushijima, Michiie Sakamoto, Hitoshi Tsuda, Setsuo Hirohashi

Journal:

Year:

1999

Language:

english

File:

PDF, 117 KB

english, 1999

15

Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas

Yoshimasa Saito, Yae Kanai, Tohru Nakagawa, Michiie Sakamoto, Hidetsugu Saito, Hiromasa Ishii, Setsuo Hirohashi

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 240 KB

english, 2003

16

Promoter hypermethylation of the potential tumor suppressor DAL-1/4.1B gene in renal clear cell carcinoma

Daisuke Yamada, Shinji Kikuchi, Yuko N. Williams, Mika Sakurai-Yageta, Mari Masuda, Tomoko Maruyama, Kyoichi Tomita, David H. Gutmann, Tadao Kakizoe, Tadaichi Kitamura, Yae Kanai, Yoshinori Murakami

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 801 KB

english, 2006

17

Regional DNA hypermethylation and DNA methyltransferase (DNMT) 1 protein overexpression in both renal tumors and corresponding nontumorous renal tissues

Eri Arai, Yae Kanai, Saori Ushijima, Hiroyuki Fujimoto, Kiyoshi Mukai, Setsuo Hirohashi

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 321 KB

english, 2006

18

Genome-wide DNA methylation profiles in liver tissue at the precancerous stage and in hepatocellular carcinoma

Eri Arai, Saori Ushijima, Masahiro Gotoh, Hidenori Ojima, Tomoo Kosuge, Fumie Hosoda, Tatsuhiro Shibata, Tadashi Kondo, Sana Yokoi, Issei Imoto, Johji Inazawa, Setsuo Hirohashi, Yae Kanai

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 312 KB

english, 2009

19

Carcinogenetic risk estimation based on quantification of DNA methylation levels in liver tissue at the precancerous stage

Ryo Nagashio, Eri Arai, Hidenori Ojima, Tomoo Kosuge, Yutaka Kondo, Yae Kanai

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 1.15 MB

english, 2011

20

Dicer is required for proper liver zonation

Shigeki Sekine, Reiko Ogawa, Michael T Mcmanus, Yae Kanai, Matthias Hebrok

Journal:

The Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 701 KB

english, 2009

21

Histological prognostic parameters for adenocarcinoma of the pancreatic head. Proposal for a scoring system for prediction of outcome

Tetsuya Nakatsura, Takahiro Hasebe, Yoshitaka Tsubono, Munemasa Ryu, Taira Kinoshita, Noriaki Kawano, Masaru Konishi, Tomoo Kosuge, Yae Kanai, Kiyoshi Mukai

Journal:

Journal of Hepato-Biliary-Pancreatic Sciences

Year:

1997

Language:

english

File:

PDF, 1.65 MB

english, 1997

22

Local recurrence after conservative surgery without postoperative radiation for pure tubular carcinoma of the breast: A case report with reference to multifocality of tubular carcinoma

Keiichi Okano, Takashi Fukutomi, Hitoshi Tsuda, Sadako Akashi-Tanaka, Takeshi Nanasawa, and Yae Kanai

Journal:

Year:

1998

Language:

english

File:

PDF, 882 KB

english, 1998

23

Apocrine carcinoma of the breast: Clinicopathological analysis and histological subclassification of 12 cases

Kaneyuki Matsuo, Takashi Fukutomi, Hitoshi Tsuda, Yae Kanai, Sadako Akashi-Tanaka, Takeshi Nanasawa

Journal:

Year:

1998

Language:

english

File:

PDF, 1.53 MB

english, 1998

24

Japanese late-onset breast cancer families: Their clinicopathological characteristics and absence ofBRCA1andBRCA2germline mutations

Takehiro Okumura, Takashi Fukutomi, Hitoshi Tsuda, Yae Kanai, Toshikazu Ushijima, Sadako Akashi-Tanaka, Takeshi Nanasawa

Journal:

Year:

1998

Language:

english

File:

PDF, 353 KB

english, 1998

25

Bilateral nonpalpable breast carcinomas in a patient withbrca2germ line mutation and past history of osteosarcoma

Toshiya Kuno, Takashi Fukutomi, Sadako Akashi-Tanaka, Takeshi Nanasawa, Yae Kanai, Hitoshi Tsuda, Tadashi Nomizu, Yoshio Miki

Journal:

Year:

1999

Language:

english

File:

PDF, 1.09 MB

english, 1999

26

Insulin-dependent diabetic mastopathy : A case report

Toshiya Kuno, Takashi Fukutomi, Sadako Akashi-Tanaka, Takeshi Nanasawa, Yae Kanai, Hitoshi Tsuda

Journal:

Year:

1997

Language:

english

File:

PDF, 1003 KB

english, 1997

27

Solid–pseudopapillary neoplasms of the pancreas in men and women: do they differ?

Yu Takahashi, Nobuyoshi Hiraoka, Kaoru Onozato, Tatsuhiro Shibata, Tomoo Kosuge, Yuji Nimura, Yae Kanai, Setsuo Hirohashi

Journal:

Virchows Archiv

Year:

2006

Language:

english

File:

PDF, 490 KB

english, 2006

28

Esophageal melanomas harbor frequentNRASmutations unlike melanomas of other mucosal sites

Shigeki Sekine, Yukihiro Nakanishi, Reiko Ogawa, Satoko Kouda, Yae Kanai

Journal:

Virchows Archiv

Year:

2009

Language:

english

File:

PDF, 210 KB

english, 2009

29

Alterations in gene expression associated with the overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, during human hepatocarcinogenesis

Yae Kanai, Yoshimasa Saito, Saori Ushijima, Setsuo Hirohashi

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2004

Language:

english

File:

PDF, 287 KB

english, 2004

30

Mice-lacking LMP2, immuno-proteasome subunit, as an animal model of spontaneous uterine leiomyosarcoma

Takuma Hayashi, Akiko Horiuchi, Kenji Sano, Nobuyoshi Hiraoka, Yae Kanai, Tanri Shiozawa, Susumu Tonegawa, Ikuo Konishi

Journal:

Year:

2010

Language:

english

File:

PDF, 290 KB

english, 2010

31

Point Mutation of the E–Cadherin Gene in Invasive Lobular Carcinoma of the Breast

Yae Kanai, Tatsuya Oda, Hitoshi Tsuda, Atsushi Ochiai, Setsuo Hirohashi

Journal:

Year:

1994

File:

PDF, 557 KB

1994

32

E-Cadherin Gene Mutations in Signet Ring Cell Carcinoma of the Stomach

Hiromi Muta, Masayuki Noguchi, Yae Kanai, Atsushi Ochiai, Hajime Nawata, Setsuo Hirohashi

Journal:

Year:

1996

File:

PDF, 367 KB

1996

33

Aberrant DNA Methylation on Chromosome 16 Is an Early Event in Hepatocarcinogenesis

Yae Kanai, Saori Ushijima, Hitoshi Tsuda, Michiie Sakamoto, Takashi Sugimura, Setsuo Hirohashi

Journal:

Year:

1996

File:

PDF, 528 KB

1996

34

Increased DNA Methyltransferase Expression Is Associated with an Early Stage of Human Hepatocarcinogenesis

Lin Sun, Ai-Min Hui, Yae Kanai, Michiie Sakamoto, Setsuo Hirohashi

Journal:

Year:

1997

File:

PDF, 545 KB

1997

35

Expression of CD44 Variants and Its Association with Survival in Pancreatic Cancer

Takuji Gotoda, Yasuhiro Matsumura, Hitoshi Kondo, Daizo Saitoh, Yasuhiro Shimada, Tomoo Kosuge, Yae Kanai, Tadao Kakizoe

Journal:

Year:

1998

Language:

english

File:

PDF, 408 KB

english, 1998

36

β-Catenin Accumulation and Mutation of Exon 3 of the β-Catenin Gene in Hepatocellular Carcinoma

Yutaka Kondo, Yae Kanai, Michiie Sakamoto, Takuya Genda, Masashi Mizokami, Ryuzo Ueda, Setsuo Hirohashi

Journal:

Year:

1999

Language:

english

File:

PDF, 3.79 MB

english, 1999

37

Disruption of E-Cadherin-mediated Cell Adhesion Systems in Gastric Cancers in Young Patients

Atsushi Saito, Yae Kanai, Chihaya Maesawa, Atsushi Ochiai, Akira Torii, Setsuo Hirohashi

Journal:

Year:

1999

Language:

english

File:

PDF, 4.66 MB

english, 1999

38

Cell adhesion system and human cancer morphogenesis

Setsuo Hirohashi, Yae Kanai

Journal:

Year:

2003

Language:

english

File:

PDF, 1.07 MB

english, 2003

39

Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas

Dun-Fa Peng, Yae Kanai, Morio Sawada, Saori Ushijima, Nobuyoshi Hiraoka, Tomoo Kosuge, Setsuo Hirohashi

Journal:

Year:

2005

Language:

english

File:

PDF, 241 KB

english, 2005

40

Array-based comparative genomic hybridization analysis of high-grade neuroendocrine tumors of the lung

Wei-Xia Peng, Tatsuhiro Shibata, Hiroto Katoh, Akiko Kokubu, Yoshihiro Matsuno, Hisao Asamura, Ryosuke Tsuchiya, Yae Kanai, Fumie Hosoda, Tokuki Sakiyama, Misao Ohki, Issei Imoto, Johji Inazawa, Setsu

Journal:

Year:

2005

Language:

english

File:

PDF, 247 KB

english, 2005

41

Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: Identification of genetic indicators that predict patient outcome

Panayiotis Loukopoulos, Tatsuhiro Shibata, Hiroto Katoh, Akiko Kokubu, Michiie Sakamoto, Ken Yamazaki, Tomoo Kosuge, Yae Kanai, Fumie Hosoda, Issei Imoto, Misao Ohki, Jyoji Inazawa, Setsuo Hirohashi

Journal:

Year:

2007

Language:

english

File:

PDF, 366 KB

english, 2007

42

Intraductal carcinoma component as a favorable prognostic factor in biliary tract carcinoma

Hidenori Ojima, Yae Kanai, Motoki Iwasaki, Nobuyoshi Hiraoka, Kazuaki Shimada, Tsuyoshi Sano, Yoshihiro Sakamoto, Minoru Esaki, Tomoo Kosuge, Michiie Sakamoto, Setsuo Hirohashi

Journal:

Year:

2009

Language:

english

File:

PDF, 280 KB

english, 2009

43

Quantitative proteomics using formalin-fixed paraffin-embedded tissues of oral squamous cell carcinoma

Ayako Negishi, Mari Masuda, Masaya Ono, Kazufumi Honda, Miki Shitashige, Reiko Satow, Tomohiro Sakuma, Hideya Kuwabara, Yukihiro Nakanishi, Yae Kanai, Ken Omura, Setsuo Hirohashi, Tesshi Yamada

Journal:

Year:

2009

Language:

english

File:

PDF, 2.44 MB

english, 2009

44

Characteristics of prostate cancers found in specimens removed by radical cystoprostatectomy for bladder cancer and their relationship with serum prostate-specific antigen level

Tohru Nakagawa, Yae Kanai, Motokiyo Komiyama, Hiroyuki Fujimoto, Tadao Kakizoe

Journal:

Year:

2009

Language:

english

File:

PDF, 846 KB

english, 2009

45

Genome-wide DNA methylation profiles in precancerous conditions and cancers

Journal:

Year:

2010

Language:

english

File:

PDF, 2.12 MB

english, 2010

46

Expression of SLCO1B3 is associated with intratumoral cholestasis and CTNNB1 mutations in hepatocellular carcinoma

Shigeki Sekine, Reiko Ogawa, Hidenori Ojima, Yae Kanai

Journal:

Year:

2011

Language:

english

File:

PDF, 599 KB

english, 2011

47

Overexpression of α-methylacyl-CoA racemase is associated with CTNNB1 mutations in hepatocellular carcinomas

Shigeki Sekine, Reiko Ogawa, Hidenori Ojima, Yae Kanai

Journal:

Year:

2011

Language:

english

File:

PDF, 1020 KB

english, 2011

48

Leiomyosarcoma of the renal vein: Arterial encasement on contrast-enhanced dynamic computed tomography

TETSUO MAEDA, UKIHIDE TATEISHI, HIROYUKI FUJIMOTO, YAE KANAI, KAZURO SUGIMURA, YASUAKI ARAI

Journal:

International Journal of Urology

Year:

2006

Language:

english

File:

PDF, 154 KB

english, 2006

49

Primary adenocarcinoma of the rete testis with preceding diagnosis of pulmonary metastases

TOHRU NAKAGAWA, NOBUYOSHI HIRAOKA, FUMIE IHARA, MOTOKIYO KOMIYAMA, YAE KANAI, YOSHIHIRO MATSUNO

Journal:

International Journal of Urology

Year:

2006

Language:

english

File:

PDF, 396 KB

english, 2006

50

Loss of blood group A antigen expression in bladder cancer caused by allelic loss and/or methylation of the ABO gene

Chihara, Yoshitomo, Sugano, Kokichi, Kobayashi, Ayumi, Kanai, Yae, Yamamoto, Hidenobu, Nakazono, Masaaki, Fujimoto, Hiroyuki, Kakizoe, Tadao, Fujimoto, Kiyohide, Hirohashi, Setsuo

Journal:

Laboratory Investigation

Year:

2005

Language:

english

File:

PDF, 307 KB

english, 2005

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